Oral administration is a method of delivering drugs or substances into the body through the mouth, typically in the form of pills, capsules, liquids, or sublingual tablets. This route of administration is commonly used due to its convenience, ease of use, and high patient compliance. The oral route allows for drugs to be absorbed through the gastrointestinal tract and distributed throughout the body to reach the target site of action. However, factors such as first-pass metabolism, variability in absorption rates, and potential degradation in the gastrointestinal tract can affect the effectiveness of orally administered drugs. Researchers in this area focus on optimizing drug formulations, improving bioavailability, and enhancing drug delivery mechanisms to overcome these challenges and improve the efficacy of oral medications.